![]() ![]() Investigating global RNA methylation in lung tissue may uncover new mechanisms underlying differences for age-related disparities in lung health, especially differences by sex and race. Public Health RelevanceĪging associates with changes in molecular features in the lung and understanding the normal ranges of age- related variability may inform insights into normal lung biology and resilience. This proposal is responsive to PA-19-049 (New Research Directions to Advance the NHBLI Strategic Vision Normal Biology) by modeling aging associated non-sequence variation of RNA in lung tissue from individuals with normal lung function. This project will address whether RNA methylation captures normal aging in the lung and will support more in-depth evaluations of the epitranscriptome as a marker of lung health. There are no published studies of RNA methylation and aging in the normal lung. We will investigate global RNA methylation through the following Specific Aims : 1) Quantification of global N6-methyl-adenosine in lung tissue from 400 individuals with normal spirometry from the Lung Tissue Research Consortium, exploring variability of RNA methylation with age, with additional consideration of sex and race associated variability 2) Identification of genetic variation that associates with RNA methylation 3)Evaluation of RNA methylation as a predictor of gene expression and a contributor to gene regulatory network signatures in lung tissue. Given the growing evidence that normal aging has a cumulative molecular impact, considering age-related changes to the epitranscriptome may advance insights into age-related resilience in the lung. ![]() We hypothesize that differential RNA methylation in lung tissue may represent a new research direction for advancing understanding of normal lung biology and genomics changes with aging. N6-methyl-adenosine (m6A) is the most studied of these RNA modifications, but aging-related global RNA methylation in lung tissue has not been explored. Epitranscriptomics refers to studies of modifications of RNA. Epigenetic marks, non-sequence based variations in the human genome, have been identified as important molecular hallmark of normal aging, with investigations mainly focused on DNA, not RNA, methylation. Normal aging of the pulmonary system associates with a multitude of physiologic, anatomic and molecular changes in the lung. ![]()
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![]() ![]() Powerful MIDI note manipulation tools and an improved editing workflow help you create new musical ideas fast. Then use the Melody- or Drums-to-MIDI feature to turn your recordings into MIDI clips that you can edit and reuse with any sound. Your voice is the new keyboard: sing, beatbox, tap a rhythm on your desk, or play any solo instrument to capture your musical ideas as they come. Sketch out ideas quickly by singing (or beatboxing) into Live and converting your recording to MIDI. Or simply seed your creativity with inspiring, natural-feeling MIDI grabbed directly from the most exciting parts of your music collection. Speed up your remixing work by using Harmony-to-MIDI to get the notes and chords from the original audio stems. Convert your favorite drum break with the Drums-to-MIDI feature and reuse it with your own sounds. Live 9's new tools for converting audio to MIDI give you unprecedented flexibility to extract musical ideas from your samples and build upon them. Live's studio effects - Compressor, Gate and EQ Eight - have been improved with new displays, enhanced controls and better sound, making it easier to see and hear your changes. Live's new Glue Compressor, developed in collaboration with Cytomic, is modeled on a classic 80s console bus compressor, both for its great sound and also to provide musical results with a simple set of controls. The new analog-modeled Glue Compressor and redesigned studio effects help you get a better sound in less time. All sounds are organized for Live 9's new browser and work seamlessly with all common hardware controllers. Live's library includes new Instrument Racks and sounds to get you going fast. Search as you type, navigate from the keyboard and sort items by various categories. Drag and drop folders into the browser from anywhere on your computer. Live's new browser puts all of your instruments and effects, samples, Packs and VST/Audio Units plug-ins in one easy-to-navigate view. ![]() With Live's new browser, spend less time finding sounds and more time making music. The automation comes with them, making it easier than ever to move from improvising to arranging and back. In one click, create new Session View scenes from your Arrangement tracks, or drag and copy individual clips from Arrangement to Session. Edit automation curves with the mouse to create smooth mix transitions or radical parameter changes in your clips. In Live 9, you can now record parameter changes directly into Session View for even more flexibility. ![]() Live's unique Session View makes it easy to improvise with musical ideas. Version 9 enhances the Ableton vision of creative, real-time digital music with a wealth of improved techniques, effects, and workflow improvements: This makes it a perfect creative tool for studios, beat creators, DJs, sound designers, and anyone who wants to have fun producing music. Either view you use is simple and basic enough to make your tasks simple and efficient, which is especially useful during a live performance. It will record all your actions as you improvise in the Session View, allowing you to edit them whenever you like. The Arrangement View takes a more traditional, timeline-based approach to multitrack recording, MIDI sequencing, and other music production tasks. Then you can play your musical ideas in any order or any time you wish. Each cell in the Session View grid can hold a recording, MIDI file, or any other musical idea, whether they're recorded on the spot or dragged in from the browser. You can work out new ideas and improvise in a free and easy production environment. ![]() The Session View is essentially a musical scratch pad. One way that Ableton Live software has an advantage over other DAWs is its extremely fluid GUI that allows you to do all your work within a single window. There are 3 versions of Live 9, this is the Standard version and includes all software features, 3 instruments, 37 effects, and over 1100 sounds (11GB). With Live 9 you can easily browse for new sounds, instantly capture your performance, record automation directly into clips, enhance your sound with improved studio effects, and then take your performance straight to the stage. The developers at Ableton have added a host of upgrades to their flagship software. JBL PRX412M - 12" 2-way Stage Monitor Ableton Live 9 is the latest iteration of one of the best performance based DAWs available on the market today. ![]() ![]() ![]() An expertly written resume complete with a sleek design and optimized resume keywords could still fall short if the formatting isn’t ATS compliant. If you’re uploading your resume into an online form as part of your job application, it is critical for your resume template to be compatible with applicant tracking systems (ATS). Jobscan Widget Embed Jobscan into your site to increase engagement and authority.Affiliates Join as an affiliate partner and earn a commission.Career Coaches Special pricing and powerful analytics for coaches.Business Powerful tools for career services and staffing businesses and associations.NGOs Partnerships to benefit non-profit organizations that help underserved jobseekers.Government Special pricing for government outplacement and career services centers.Universities Improve student employment outcomes and coaching efficiency. ![]() Customer Stories See how Jobscan helped job seekers get their dream job.Learning Center In-depth guides on optimizing your resume, cover letter, and LinkedIn profile.Career Change Guides Expert advice on how to make a career change with guides for every step of the journey.Guides on headlines, summaries, work experience, and more. LinkedIn Guides Learn how to craft the perfect LinkedIn profile.Job Search Advice Tips and hacks for saving time and getting better results in your job search.Cover Letter Guides Guides, tips, and advice for writing a convincing cover letter that makes you stand out from the crowd. ![]()
![]() ![]() You can play almost all of the commercial Nintendo DS games with the No$GBA emulator on your PC, so this kills two birds with one stone. Nintendo DS emulators are a very rare software nowadays and one that is available for free almost seems too good to be true. The best thing about No$GBA apart from the amazing GBA emulation and online connectivity is the feature that it also doubles as a Nintendo DS emulator. You can use this connectivity to trade pokemon and fight other trainers in all the Pokemon games for GBA but you can also utilize the connectivity for other games as well. This is achieved by mimicking the GBA link connectivity so you can connect with other gamers via internet or local network and enjoy your games together. The best thing No$GBA is the fact that it also includes connectivity with other No$GBA emulators so you can enjoy multiplayer games. No$GBA also known as No Cash GBA emulator is another one of the top-notch emulators for GBA systems. Fullscreen mode lets you stretch all your games to a full screen mode but that will pixelate the graphics due to smaller screen size of the GBA and other Gameboy games. Joystick support lets you enjoy all the amazing games with a joystick. You can export all your saved files and play them in other emulators as well. Supports full save state feature and you can also speed up your gameplay with just a press of a single button. VBA-M is compatible with all GB (GameBoy), GBC (GameBoy Color), and GBA (GameBoy Advance) roms. VBA-M is the all new version that has continued the legacy of VBA and even brought some cool new features to this emulator to make it even more amazing for the gamers. It had a long successful streak but in 2004 the developer behind this iconic emulator gave up on it which led to many other versions of the VBA emulator developed by different developers. Visual Boy Advance commonly known as VBA became one of the first and fully functional Game Boy advance emulators out in the market and it has always been available for free as a download. ![]() ![]() ![]() The first official flag of the American Revolution was the “Grand Union” flag first flown by General Washington on January 2nd 1776 at Cambridge Massachusetts.Ĭoincidentally it was also the same EXACT flag as the BRITISH-EAST INDIA COMPANY. Was the flag with vertical stripes a way of rebelling against the British East India Company? The British-East India Company flag had red and white horizontal stripes with the Union Jack in the upper left-hand corner. Why did they choose red and white vertical stripes as their symbol? The "rebellious stripes", as the flag came to be called, was the original flag used by the Sons of Liberty, and it had 9 red and white vertical stripes! So, the original “common law flag” was first raised over the Liberty Tree in Boston. The petition asserted that extending the courts of ADMIRALTY, the law of the seas, in order to prosecute the Act undermined "the rights and liberties" of the colonists. A petition of rights and grievances was drawn up declaring that the colonists "were entitled to all the inherent rights and liberties of natural born subjects." The colonies also declared that "no taxes ever have been, or can be constitutionally imposed upon them, but by their respective legislatures," and that it “was unreasonable and inconsistent for the people of Great Britain to grant to His Majesty the property of the colonists." The Stamp Act rebellion initiated the Stamp Act Congress, which gathered representatives from nine of the thirteen colonies. The Elm tree Oliver was hung on became known as the "Liberty Tree". Eventually, Oliver resigned, his home looted, and the stamps destroyed. The Stamp Act created great unrest in America, especially in Boston, where an effigy of the local stamp agent, Andrew Oliver, was hanged and burned. The Stamp Act was imposed by the British Parliament to tax all forms of legal documents within their American colonies. In Boston, the Sons of Liberty were the original revolutionary group who sparked the initial rebellion against the British in 1765. Why did Wolcott choose to turn the horizontal stripes of Old Glory ninety degrees? We need to return to the beginnings of the American Revolution to satisfy this query. Where did Wolcott get the idea of using vertical stripes from? Richardson required all customhouses to display the Civil Flag. The practice of using the Customs Flag as a Civil Flag became encoded law in 1874 when Treasury Secretary William. By the Law of the Flag, the vertical striped design denoted Roman Civil jurisdiction within Federal territories rather than Military jurisdiction under Admiralty law. ![]() The Civil Flag had red and white vertical stripes with blue stars on a white background. The use of the Civilian Flag also spread to Merchants and Common citizens to symbolize their Constitutional rights. In the early days of our nation, horizontal stripes became the accepted practice for use over military posts, and vertical stripes were used over civilian establishments. The Revenue Cutter ensign had vertical stripes to denote civilian authority under the Treasury Department rather than military authority under the War Department. The original purpose of the Revenue Cutter was to collect tariffs and other taxes that were imposed on foreign goods. This new flag was actively flown on Revenue Cutters, what we now call Coast Guard Cutters. This was done so that non-military ships would be easily recognized and not fired upon as they tried to hail and board foreign vessels. It is significant that Wolcott’s new civilian flag had vertical stripes, not horizontal. Wolcott's proposal featured: An ensign, consisting of sixteen alternating red and white stripes representing the number of states that had joined the Union by 1799 and the Union, represented by the small rectangle in the upper left corner, with its Arms (an Eagle) of the United States in dark blue on a white field. the Secretary of the Treasury under John Adams. Flag, which denoted civilian versus military purposes, was designed in 1799 by Oliver Wolcott Jr. ![]() ![]() ![]() Kashi Crunchy Chocolate Chip chia granola bars.KIND bars (nuts and spices variety pack).Image credit: Jamieanne via Flickr CC BY-ND 2.0 No.4: Food to take on a Road Trip from the Bakery or Grocery Store These non refrigerated road trip food choices will keep you going, when there’s no other options. Ready to eat soups from the pantry (if you have access to a microwave enroute).Cup of soup in a packet (add hot water).Cup of noodles (healthy brands, without MSG seasoning) – BYO hot water, or ask for a cup of hot water at a fast food restaurant or fuel station.Real fruit roll ups (not the junk food version).Small pots of dried cereal (cheerios, nutrigrain).Here’s more somewhat healthy non refrigerated snacks for travel. MORE ideas for non perishable snacks for travel Single serve of ready to eat porridge cups or chia pudding from the pantry.Dried apple snacks, dried banana, dried peaches, dried mango slices.Carman’s nut bars and Carman’s muesli bars.Homemade energy balls with seeds, nut butter and honey.Packaged “bliss balls” – date and cashew nut balls.Mini flavored cans, tins or pouches of tuna (or salmon).Cashew nut butter or sunflower seed butter- with slices of apple or carrot veggie sticks.Beef jerky (try the COFFEE jerky, and the vegemite jerky!).Rice cakes or corn crackers, saltine crackers, multigrain crackers, or sao crackers, topped with peanut butter, apple sauce, or tahini or mashed avocado or tinned fish.When you don’t have a cooler and need non perishable healthy snacks that don’t need to be kept in the fridge, try these healthy road trip snacks from the pantry: Image credit: Mike Mozart via Flickr CC BY-2.0 No.3: Best Non Perishable Road Trip Food Water crackers (and cubes of cheese and dip- see below).Image credit: Torbakhopper via Flickr CC BY-2.0 No.2: Dry Crackers and Biscuits RELATED: The Ultimate “Road Trip Food List” (update coming soon) dried fruit rolls (whole foods section).dried fruits – raisins, sultanas, cranberries, dried blueberries, dried mango, dried bananas, dried apple rings. ![]()
![]() ![]() ![]() ![]() Donkey- Name your cat, Donkey, if they have a goofy and fun-loving personality!.Daisy- A cheerful floral name is perfect for a cat that makes you smile.Colby- This name works just as well for a male or female cat.Cocoa- If you adopted your cat during a winter month, name them for a delicious winter drink!.Claw- Cats are known for whipping out their sharp claws to climb or scratch. ![]() Charlie- You cannot go wrong with this timeless and sweet name for a boy cat.Cheetah- Name your cat after one of their bigger relatives- the cheetah!.Chandler- Not only is this a gender-neutral name choice, but it’s also an excellent option for any big fans of the tv show Friends.Carol- Carol is a traditional and timeless name for a female.Canyon- An artsy name for the nature-loving pet lover.If this embodies your kitty’s personality, this will make a fun name! Cactus- Some cats are like a cactus- prickly on the outside by cuddly on the inside.Burrito- The logic behind this one? Cats are warm and cuddly and love to be wrapped up in blankets like a burrito.Bruno- Name your cat Bruno if they are independent and determined.Brody- This is a boy name that has grown in popularity in recent years.Bowie- Such a fun name for a big David Bowie fan.Boots- This would make a great name if your cat has a different coloring around their toes or feet.Blaze- Consider this name for your grey tabby if they have a spunky personality.It also connotes a steel blade, which is an excellent tie-in for a grey colored cat. Blade- A strong name for a tough boy cat.Biscuit- Biscuit is an adorable name, perfect for a cat who lives in the South. Binx- This is a quirky and original cat name for all the Halloween movie Hocus Pocus lovers.Beast- A firm, masculine name for a cat that never seems to run out of energy.Cats are fur babies, so it’s only fitting! Bébé- This is the French word for baby.Astro- Tabby cats are known for having beautiful color variations in their fur, just like beautiful color variations in the night sky.This is the perfect name for a pure and noble cat. Aslan- Aslan in The Lion, The Witch, and The Wardrobe has to be one of the most famous cats in the literary world.Ash- If you want to pay homage to your cat’s beautiful fur color, this is a great name choice!.Ajax- A fierce and robust name with origins in Greek mythology, this name would be perfect for a brave cat.Angel- This name is ideal for a docile and well-behaved cat.The name is associated with the sun god, making it perfect for a fiery kitty. Aiden- Aiden is a strong name with Celtic origins.To make this process easier, we have put together a comprehensive list from A-Z of our favorite cat names for a grey tabby cat! Additionally, you want to choose a name that fits your cat’s look physically and also matches their personality. Your cat’s name is a long-term decision, and you want to love the name you pick for many years to come. If you prefer the visual experience we hand selected our favorites from this list in this video.Picking a name for your grey tabby cat is an important matter. And hopefully, this article brings benefits to inspire you to name your cute tabby cat. Tabby cats are special due to their unique pattern and have one genetic trait. The Cheshire Cat (Alice’s Adventures in Wonderland)Ĭheck the full list of gender neutral tabby cat names.Tabby (First Pet to President Abraham Lincoln).If you haven’t found the best name yet, you suggest you visit our orange female tabby cat names and orange tabby cat names Grey Tabby Cat Names įind out more about our brown tabby cat names list here Famous Tabby Cats Oliver (Oliver & Company) Here are more of our male orange tabby cat name ideas Female Orange Tabby Cat Names Orange Tabby Cat Names Male Orange Tabby Cat Names Female Tabby Cat Names ĭiscover more about female tabby cat names here. You can find more male tabby cat names here. 10 Gender Neutral Tabby Cat Names Male Tabby Cat Names ![]() ![]() ![]() Using Photoshop Express Photo Editor on PC :.On your computer, goto the Downloads folder » click to install Bluestacks.exe or Nox.exe » Accept the License Agreements » Follow the on-screen prompts to complete installation. Install the emulator on your PC or Mac:.Download Bluestacks Pc or Mac software Here >. We recommend Bluestacks because you can easily find solutions online if you run into problems while using it. Download an Android emulator for PC and Mac:.Liked Photoshop Express Photo Editor? here are 5 Photo & Video apps like Canon DPP Express Express Video - Add Emoji Emoji Camera Stickers: Add Cool Emoticon smiley Flirty Expression To Your Picture Mood Expressions - Eye Color Change Picture collage features to turn photos into collages with a digital scrapbook effect.ġ2. Photoshop Express delivers a wide and diverse selection of features and effects at your fingertips.ġ1. You don’t have to be a professional photo editor to make stunning picture edits.ġ0. Upgrade to Photoshop Express Premium to access extra, exclusive features and more precise editing controls.ĩ. Fused Looks: Our newest feature lets you apply two looks filters to one photo for a rich effect.Ĩ. ![]() Create high quality images and touch up your favorite moments with our easy-to-use photo design tools on your mobile device.ħ. Photoshop Express is the photo editor and design app for users of all experience levels.Ħ. Create a photo collage, generate memes, fix and enhance your share-worthy moments for stunning social media content.ĥ. ![]() Use our photo editing app to personalize and perfect your experiences with stickers and overlays, apply blur, enhance colors and images with Looks filters.Ĥ. Tap into your creativity on the go with Photoshop Express–a fun, fast, and easy picture editor for one-touch transformations and photo edits–used by millions of creative individuals.ģ. Make photo magic happen with the Photoshop Express picture editor from Adobe - proud makers of the Photoshop family.Ģ. ![]() ![]() Q: Can I change my signature after adding it to an Excel document?Ī: Yes, you can change your signature after adding it to an Excel document using Adobe Acrobat Reader. FAQs Q: Can I add multiple signatures to an Excel document on Mac?Ī: Yes, you can add multiple signatures to an Excel document using any of the methods above. It is also recommended to use trusted and reliable software to add electronic signatures to your document. It is crucial to ensure all documents containing electronic signatures are in a secure location to prevent unauthorized access. Implications and RecommendationsĪdding a signature to your Excel document adds an extra layer of security and makes the document legally binding. The document is password-protected and cannot be edited. The document is not in an electronic format that is compatible with adding signatures.ģ. You do not have the necessary software tools to do so.Ģ. Why Can’t I Add A Signature on Excel Macġ. – Free online tools may have limited features or be unreliable. – You need to upload your document to a third-party server, which may compromise the privacy and security of your document. – Online tools offer convenience and accessibility from any computer with an internet connection. Save your document and download it back to your Mac. ![]() Drag and drop the signature onto the signature area of your document or use the online drawing tools to create a new signature.ĥ. Select where you want to add the signature on the document.Ĥ. ![]() Upload the document you want to add a signature to.ģ. Open your browser and go to an online signature tool such as DocuSign.Ģ. Here are steps to follow to add a signature using an online tool:ġ. These tools are accessible from any computer, including your Mac. Several online tools offer the feature to add electronic signatures to documents. Method 3: Adding a Signature using Online Tools – It may take a while to familiarize yourself with the many features, including adding signatures. – Acrobat Reader requires a separate download and installation. – The signature can be edited if a mistake is made or if you want to change it. – Adobe Acrobat Reader offers more features related to PDF files than Preview or other tools. Click on ‘Apply’ to insert the signature onto your document. Select how you want to sign from the options available such as window image or camera image.ĥ. Click on the ‘Fill & Sign’ icon at the top-right corner of the screen.Ĥ. Here are steps to follow to add a signature using Acrobat Reader:Ģ. Method 2: Using Adobe Acrobat ReaderĪdobe Acrobat Reader is a popular PDF viewer that comes with a feature to add electronic signatures. – The signature may not be easily editable if a mistake is made. – Preview is limited in functionality compared to other software tools. – It is easy to use because Preview comes pre-installed on all Mac computers. Adjust the signature by clicking and dragging the corners and margins.Ħ. Drag and drop the signature you want to use onto the signature area of your Excel file.ĥ. Click on the signature icon at the top-right corner of the screen.Ĥ. Open the document containing your signature, whether it is a PDF file or an image file.ģ. ![]() Open your Excel document and navigate to where you want to add a signature.Ģ. Here are steps to follow to add a signature using Preview:ġ. Preview is a great built-in tool on a Mac that offers some functionalities to help users work with PDF files. Method 1: Adding a Signature using Preview Also, verify that the document does not have any sensitive or confidential information that you do not want to share. This can be an image file or a PDF document. Adobe Acrobat Reader What requires your attention is.?īefore proceeding with any of the methods below, it is important to ensure the document containing your signature is in electronic format. Your signature in electronic format such as image or PDFĤ. To add a signature to an Excel document on a Mac, you need the following:Ģ. In this article, we will provide several methods on how to add a signature to an Excel document on your Mac. Signatures make documents legally binding and add a layer of security. However, adding a signature is essential, particularly when working with important and sensitive documents. Many people find it challenging to figure out how to add a signature to an Excel spreadsheet on Mac. Why Can’t I Add A Signature on Excel MacĪre you struggling with adding your signature to an Excel document on your Mac? You’re not alone. ![]() ![]() To view it in Finder, hold down the Option (⌥) key while clicking the Go menu, and your Library folder will appear as a menu choice. The directory Warzone 2100 can be found in your home-directory at: ~/Library/Application Support/īy default, recent version of macOS hide your account’s Library folder. Entering: %APPDATA%\Warzone 2100 Project\ into the address bar of Windows Explorer / File Explorer will browse to your Warzone directory. Hence, the default path for the Warzone 2100 configuration data on Windows Vista+ would be: C:\Users\$USER$\AppData\Roaming\Warzone 2100 Project\Warzone 2100 \īy default, the %APPDATA% folder is hidden. The directory Warzone 2100 Project\Warzone 2100 is located under the %APPDATA% folder. ![]() |
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